Two years ago Spanair flight JK-5022 crashed, killing 154 of 172 on board. According to El Paris (via Google Translate), this was at least in part due to a PC located on the ground in the headquarters of the airline. That computer was supposed to sound an alarm signal when three similar technical problems registered on the same device. While the plane that crashed had accumulated three incidents, they were not registered in time because the system was infected by malware (trojans).
Investigators believe this may be the cause of the crash. The judge said that if these three incidents had been identified earlier, the plane never would have taken off.