Logfile of HijackThis v1.99.1
Scan saved at 11:48:12, on 22.3.2008
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Microsoft Shared\VS7DEBUG\MDM.EXE
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\SOUNDMAN.EXE
C:\WINDOWS\System32\RUNDLL32.EXE
C:\Program Files\Eset\nod32kui.exe
C:\Program Files\Java\jre1.6.0_02\bin\jusched.exe
C:\WINDOWS\tsnpstd3.exe
C:\WINDOWS\vsnpstd3.exe
C:\Program Files\QuickTime\qttask.exe
C:\WINDOWS\System32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\DAEMON Tools Lite\daemon.exe
C:\Program Files\InterVideo\Common\Bin\WinCinemaMgr.exe
E:\Marta\Last.fm\LastFMHelper.exe
C:\Program Files\Eset\nod32krn.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\WINDOWS\System32\PnkBstrA.exe
C:\WINDOWS\System32\PnkBstrB.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\ICQLite\ICQLite.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Program Files\Java\jre1.6.0_02\bin\jucheck.exe
C:\Program Files\Total Commander 6.52\TOTALCMD.EXE
C:\Program Files\Winamp\winamp.exe
E:\Marta\Last.fm\LastFM.exe
C:\Program Files\Hijackthis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.sk/
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: Skype add-on (mastermind) - {22BF413B-C6D2-4d91-82A9-A0F997BA588C} - C:\Program Files\Skype\Toolbars\Internet Explorer\SkypeIEPlugin.dll
O2 - BHO: BitComet ClickCapture - {39F7E362-828A-4B5A-BCAF-5B79BFDFEA60} - E:\Marta\BitComet\tools\BitCometBHO_1.1.11.30.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [SoundMan] SOUNDMAN.EXE
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\System32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [CloneCDTray] "C:\Program Files\CloneCD\CloneCDTray.exe" /s
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [nod32kui] "C:\Program Files\Eset\nod32kui.exe" /WAITSERVICE
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_02\bin\jusched.exe"
O4 - HKLM\..\Run: [tsnpstd3] C:\WINDOWS\tsnpstd3.exe
O4 - HKLM\..\Run: [snpstd3] C:\WINDOWS\vsnpstd3.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\ctfmon.exe
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [DAEMON Tools Lite] "C:\Program Files\DAEMON Tools Lite\daemon.exe"
O4 - HKCU\..\RunOnce: [ICQ Lite] C:\Program Files\ICQLite\ICQLite.exe -trayboot
O4 - Startup: Adobe Gamma.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Startup: Last.fm Helper.lnk = E:\Marta\Last.fm\LastFMHelper.exe
O4 - Global Startup: Akcelerátor spuštění AutoCADu.lnk = C:\Program Files\Common Files\Autodesk Shared\acstart17.exe
O4 - Global Startup: InterVideo WinCinema Manager.lnk = C:\Program Files\InterVideo\Common\Bin\WinCinemaMgr.exe
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O9 - Extra button: Skype - {77BF5300-1474-4EC7-9980-D32B190E9B07} - C:\Program Files\Skype\Toolbars\Internet Explorer\SkypeIEPlugin.dll
O9 - Extra button: Zdroje informací - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: ICQ Lite - {B863453A-26C3-4e1f-A54D-A2CD196348E9} - C:\Program Files\ICQLite\ICQLite.exe
O9 - Extra 'Tools' menuitem: ICQ Lite - {B863453A-26C3-4e1f-A54D-A2CD196348E9} - C:\Program Files\ICQLite\ICQLite.exe
O9 - Extra button: Related - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra 'Tools' menuitem: Show &Related Links - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra button: BitComet - {D18A0B52-D63C-4ed0-AFC6-C1E3DC1AF43A} - res://E:\Marta\BitComet\tools\BitCometBHO_1.1.11.30.dll/206 (file missing)
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft.com/fwlink/?linkid=39204
O16 - DPF: {62789780-B744-11D0-986B-00609731A21D} (Autodesk MapGuide ActiveX Control) - http://195.28.70.134/kapor2/lib/mgaxctrl.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{26633E83-F75C-4BE2-BDB3-5B1AD824CF5E}: NameServer = 172.30.0.1
O17 - HKLM\System\CS1\Services\Tcpip\..\{26633E83-F75C-4BE2-BDB3-5B1AD824CF5E}: NameServer = 172.30.0.1
O17 - HKLM\System\CS2\Services\Tcpip\..\{26633E83-F75C-4BE2-BDB3-5B1AD824CF5E}: NameServer = 172.30.0.1
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~1\COMMON~1\Skype\SKYPE4~1.DLL
O23 - Service: Adobe LM Service - Adobe Systems - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe
O23 - Service: Autodesk Licensing Service - Autodesk - C:\Program Files\Common Files\Autodesk Shared\Service\AdskScSrv.exe
O23 - Service: NOD32 Kernel Service (NOD32krn) - Eset - C:\Program Files\Eset\nod32krn.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\System32\nvsvc32.exe
O23 - Service: PnkBstrA - Unknown owner - C:\WINDOWS\System32\PnkBstrA.exe
O23 - Service: PnkBstrB - Unknown owner - C:\WINDOWS\System32\PnkBstrB.exe

what should I do? please help!!

And what do you want us to do?
A hijack log tells us nothing because it is in the wrong section.
Also, we are not good at guessing what issues you are having.

Do you have a virus, malware, spyware, won't boot, can't get into safe mode???
There could be a zillion things that you are asking, and we haven't a clue what you want.

Oh and welcome to Geeks to Go.