Hi Jemc2 and welcome to Geeks To Go Forums.
You asay your drive is no longer registred as "C:\" and now its "F:\". Ok start off by going to:
> Start
> Control Panel
> Administrative Tools
> Component Managment
When the program has opened the menu on the left go down to "Storage" you may have to extend the tree, then click on "Disk Managment"
On the right there will be al ist of drives, right click on the drive letter "F:\" and say "Change drive letters and paths...." When the window opens click on "change". From there it is self explanitory. I hope this works for you, if you run into any problems let me know.
Also let me know if this worked. Thanks