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ANOTHER virus/spyware?!

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Below is my hijack this log. I'd be very grateful if anyone could tell me what is causing all my pop ups, and what is messing with my internet explorer security settings. I have a feeling programs like IST bar and Internet Optimiser might have something to do with it! Thanks for your help!

Logfile of HijackThis v1.99.1
Scan saved at 10:41:56, on 20/04/2005
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\Program Files\Sophos SWEEP for NT\SWNETSUP.EXE
C:\Program Files\Sophos SWEEP for NT\SWEEPSRV.SYS
C:\Program Files\Java\jre1.5.0_01\bin\jusched.exe
C:\Program Files\AutoUpdate\AutoUpdate.exe
C:\Program Files\Sophos SWEEP for NT\ICMON.EXE
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.co.uk/
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.co.uk/
R3 - Default URLSearchHook is missing
N3 - Netscape 7: user_pref("browser.startup.homepage", "www.google.co.uk"); (C:\Documents and Settings\Rich Mott\Application Data\Mozilla\Profiles\default\78zcjwop.slt\prefs.js)
N3 - Netscape 7: user_pref("browser.search.defaultengine", "engine://C%3A%5CProgram%20Files%5CNetscape%5CNetscape%5Csearchplugins%5CSBWeb_01.src"); (C:\Documents and Settings\Rich Mott\Application Data\Mozilla\Profiles\default\78zcjwop.slt\prefs.js)
O2 - BHO: BHObj Class - {00000010-6F7D-442C-93E3-4A4827C2E4C8} - C:\WINDOWS\nem220.dll
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: PCTools Site Guard - {5C8B2A36-3DB1-42A4-A3CB-D426709BBFEB} - C:\PROGRA~1\SPYWAR~1\tools\iesdsg.dll
O2 - BHO: PCTools Browser Monitor - {B56A7D7D-6927-48C8-A975-17DF180C71AC} - C:\PROGRA~1\SPYWAR~1\tools\iesdpb.dll
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [SunJavaUpdateSched] C:\Program Files\Java\jre1.5.0_01\bin\jusched.exe
O4 - HKLM\..\Run: [PcSync] PCsync.exe
O4 - HKLM\..\Run: [Internet Optimizer] "C:\Program Files\Internet Optimizer\optimize.exe"
O4 - HKLM\..\Run: [AutoUpdater] "C:\Program Files\AutoUpdate\AutoUpdate.exe"
O4 - HKLM\..\Run: [Power Scan] C:\Program Files\Power Scan\powerscan.exe
O4 - HKLM\..\Run: [Windows System Configuration] C:\WINDOWS\WINFRW.EXE
O4 - HKLM\..\Run: [Windows Security Updater] C:\WINDOWS\WINFRW.EXE
O4 - HKLM\..\RunServices: [PcSync] PCsync.exe
O4 - HKCU\..\Run: [PcSync] PCsync.exe
O4 - HKCU\..\Run: [Y00pRPa7h] maknonce.exe
O4 - HKCU\..\RunServices: [PcSync] PCsync.exe
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O4 - Global Startup: InterCheck Monitor.LNK = C:\Program Files\Sophos SWEEP for NT\ICMON.EXE
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: Spyware Doctor - {2D663D1A-8670-49D9-A1A5-4C56B4E14E84} - C:\PROGRA~1\SPYWAR~1\tools\iesdpb.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O9 - Extra 'Tools' menuitem: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O15 - Trusted Zone: http://ny.contentmatch.net (HKLM)
O16 - DPF: {04E214E5-63AF-4236-83C6-A7ADCBF9BD02} (HouseCall Control) - http://housecall-bet...all/xscan60.cab
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft....467&clcid=0x409
O16 - DPF: {31B7EB4E-8B4B-11D1-A789-00A0CC6651A8} (Cult3D ActiveX Player) - http://www.cult3d.co...wnload/cult.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupd...b?1104618298042
O16 - DPF: {79849612-A98F-45B8-95E9-4D13C7B6B35C} (Loader2 Control) - http://static.topcon...vex/website.ocx
O16 - DPF: {7C559105-9ECF-42B8-B3F7-832E75EDD959} (Installer Class) - http://www.xxxtoolba...006_regular.cab
O16 - DPF: {A18962F6-E6ED-40B1-97C9-1FB36F38BFA8} (Aurigma Image Uploader 3.0 Control) - http://www.first4fot...geUploader3.cab
O16 - DPF: {A93D84FD-641F-43AE-B963-E6FA84BE7FE7} (LinkSys Content Update) - http://www.linksysfi...ll/gtdownls.cab
O16 - DPF: {B38870E4-7ECB-40DA-8C6A-595F0A5519FF} (MsnMessengerSetupDownloadControl Class) - http://messenger.msn...pdownloader.cab
O20 - Winlogon Notify: NavLogon - C:\WINDOWS\System32\NavLogon.dll
O23 - Service: DefWatch - Unknown owner - C:\Program Files\NavNT\defwatch.exe (file missing)
O23 - Service: LexBce Server (LexBceS) - Lexmark International, Inc. - C:\WINDOWS\system32\LEXBCES.EXE
O23 - Service: MSCSPTISRV - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\MSCSPTISRV.exe
O23 - Service: Norton AntiVirus Client (Norton AntiVirus Server) - Unknown owner - C:\Program Files\NavNT\rtvscan.exe (file missing)
O23 - Service: NVIDIA Driver Helper Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\System32\nvsvc32.exe
O23 - Service: PACSPTISVR - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\PACSPTISVR.exe
O23 - Service: Sony SPTI Service (SPTISRV) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\SPTISRV.exe
O23 - Service: SonicStage SCSI Service (SSScsiSV) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\SSScsiSV.exe
O23 - Service: Sophos Anti-Virus Network (SweepNet) - Sophos Plc - C:\Program Files\Sophos SWEEP for NT\SWNETSUP.EXE
O23 - Service: Sophos Anti-Virus (SWEEPSRV.SYS) - Sophos Plc - C:\Program Files\Sophos SWEEP for NT\SWEEPSRV.SYS
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