I have been referred here from the Virus Infection Forum having completed a thorough process to try to uncover any virus or infection which might induce thios problem.
The computer is a laptop which was infected with the Zlob virus from a video codec that was downloaded. After the infection when the computer boots into normal mode and I log on the computer produces a 'Windows cannot access the specified device. You may not have the appropriate permission to access the item.'
This warning or error if you like appears whenever any program is attempted to start, .exe, .bat and .cmd files. Also cannot access most of control panel nor open a dos screen with the Start-Run process. In short just about nothing works. In safe mode however there are no issues using the same profile to log on. The profile is set up as an Adminstrator. I have reset permissions and file associations numerous times with Dial-a-fix running it from safe mode. I can access internet and run all programs from safe mode.
One interesting thing is that I found occasionally I could access a program if I clicked on the icon immediately it appears on startup - then one in ten times maybe I could get a programme to run but this functionality has now disappeared as we have been cleaning the computer.
I have tried everything I can think of but still no joy. I also set up a new user as Administrator but same issue with that account too. i do not know what else to try - it is like the registry gets hijacked as it starts up and does some permission manipulation to refuse access to everything. Any help would be much appreciated.