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Missing CD-ROM and CD-RW drives

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Virus is suspected on my machine. Hardware is ok: devices appear biefly in My Computer on startinfg machine, than dissapear. Uninstalling devies in Device Manager removes them, Add Hardware wizard finds them but fails to install them correctly (Code 39), and the yellow exclamation marks return. Have followed all possible processes as adised in HiJackThis instructions: after running Panda ActiveScan mousehs.exe appeared and started asking for access to internet.

Help in getting rid of this virus so I can backup the hard drive much appreciated please, thanks.
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Sorry, here is the logfile

Logfile of HijackThis v1.99.1
Scan saved at 09:56:30, on 03/05/2005
Platform: Windows XP (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2600.0000)

Running processes:
C:\Program Files\Zone Labs\ZoneAlarm\zlclient.exe
C:\Program Files\Thomson\SpeedTouch USB\Dragdiag.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Microsoft Office\Office\Osa.exe
C:\Program Files\Microsoft Office\Office\Findfast.exe
C:\Documents and Settings\phil clarke\Desktop\anti virus downloads\sp1aexpress_usa.exe
C:\Documents and Settings\phil clarke\Desktop\anti virus downloads\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = about:blank
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.co.uk/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.freeuk.net/
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.co.uk
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page_bak = http://www.google.co.uk/
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Local Page = C:\WINDOWS\SYSTEM\blank.htm
R3 - Default URLSearchHook is missing
F2 - REG:system.ini: UserInit=C:\WINDOWS\System32\Userinit.exe
O2 - BHO: Yahoo! Companion BHO - {02478D38-C3F9-4efb-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn\ycomp5_5_7_0.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O3 - Toolbar: Freeserve - {8B68564D-53FD-4293-B80C-993A9F3988EE} - (no file)
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\SYSTEM32\msdxm.ocx
O3 - Toolbar: Yahoo! Companion - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\ycomp5_5_7_0.dll
O4 - HKLM\..\Run: [MyWebSearch Email Plugin] C:\PROGRA~1\MYWEBS~1\bar\f.bin\mwsoemon.exe
O4 - HKLM\..\Run: [Restart WSC Setting] C:\PROGRA~1\blcorp\UWCSuite\WSC\wscrestp.exe
O4 - HKLM\..\Run: [Windows Update] vgcntfy.exe
O4 - HKLM\..\Run: [Zone Labs Client] C:\Program Files\Zone Labs\ZoneAlarm\zlclient.exe
O4 - HKLM\..\Run: [AVG7_EMC] C:\PROGRA~1\Grisoft\AVGFRE~1\avgemc.exe
O4 - HKLM\..\Run: [RemoteControl] "C:\Program Files\CyberLink\PowerDVD\PDVDServ.exe"
O4 - HKLM\..\Run: [SpeedTouch USB Diagnostics] "C:\Program Files\Thomson\SpeedTouch USB\Dragdiag.exe" /icon
O4 - HKLM\..\Run: [MsWindows Syspg] mspg32.exe
O4 - HKLM\..\RunServices: [Microsoft media services] winmplayer.exe
O4 - HKLM\..\RunServices: [Windows Update] vgcntfy.exe
O4 - HKLM\..\RunServices: [msdev] msdev.exe
O4 - HKLM\..\RunServices: [ATI Control Panel] atictlp.exe
O4 - HKLM\..\RunServices: [Realplayer One] realplay.exe
O4 - HKLM\..\RunServices: [MsWindows SysDate] sysmsvc.exe
O4 - HKLM\..\RunServices: [MICROSOFT UNPACK SYSTEM] winregs32.exe
O4 - HKLM\..\RunServices: [Sygate Personal Port] crss.exe
O4 - HKLM\..\RunServices: [MsWindows Syspg] mspg32.exe
O4 - HKLM\..\RunOnce: [Windows Update] vgcntfy.exe
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\System32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [ATI Control Panel] atictlp.exe
O4 - HKCU\..\Run: [PopUpStopperFreeEdition] "C:\PROGRA~1\PANICW~1\POP-UP~1\PSFREE.EXE"
O4 - HKCU\..\Run: [MyWebSearch Email Plugin] C:\PROGRA~1\MYWEBS~1\bar\f.bin\mwsoemon.exe
O4 - HKCU\..\Run: [Windows Update] vgcntfy.exe
O4 - HKCU\..\Run: [IncrediMail] C:\Program Files\IncrediMail\bin\IncMail.exe /c
O4 - HKCU\..\RunOnce: [Windows Update] vgcntfy.exe
O4 - Global Startup: EPSON Background Monitor.lnk = C:\ESM2\STMS.exe
O4 - Global Startup: Office Startup.lnk = C:\Program Files\Microsoft Office\Office\OSA.EXE
O4 - Global Startup: Microsoft Find Fast.lnk = C:\Program Files\Microsoft Office\Office\FINDFAST.EXE
O8 - Extra context menu item: &Add animation to IncrediMail Style Box - C:\PROGRA~1\INCRED~1\bin\resources\WebMenuImg.htm
O9 - Extra button: Real.com - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - C:\WINDOWS\System32\Shdocvw.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O14 - IERESET.INF: START_PAGE_URL=http://www.freeuk.net/
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupd...b?1113469098239
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai...all/xscan53.cab
O16 - DPF: {9A9307A0-7DA4-4DAF-B042-5009F29E09E1} (ActiveScan Installer Class) - http://www.pandasoft.../as5/asinst.cab
O16 - DPF: {CA034DCC-A580-4333-B52F-15F98C42E04C} (Downloader Class) - http://www.stopzilla...ller/dwnldr.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{2AB342B5-5CFF-4AE5-A6D0-4BEB09980D79}: NameServer =
O23 - Service: AVG7 Alert Manager Server (Avg7Alrt) - GRISOFT, s.r.o. - C:\PROGRA~1\Grisoft\AVGFRE~1\avgamsvr.exe
O23 - Service: AVG7 Update Service (Avg7UpdSvc) - GRISOFT, s.r.o. - C:\PROGRA~1\Grisoft\AVGFRE~1\avgupsvc.exe
O23 - Service: Mouse Hardware Sync (mousehs) - Unknown owner - C:\WINDOWS\System32\mousehs.exe
O23 - Service: TrueVector Internet Monitor (vsmon) - Zone Labs, LLC - C:\WINDOWS\SYSTEM32\ZONELABS\vsmon.exe
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