Being that you are dealing with Vista you will most likely have to reregister anyway due to the change of hardware. If you have no problem with formatting and doing a fresh install and have backup of all your important data. I would say go for it. Then you will have a system that can run as smoothly as possible and installing one piece of software at a time, you can then test each and make sure there are no issues before moving to the next.
Let me know how it goes and as always I will be here if you need assistance