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BankerFox.A and Win32/Nuqel.E

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Okay, so my laptop has a virus on it that doesn't allow me to run any programs basically.
When I attempt to run a program there is an error that pops up and blocks it that says...
"Application cannot be executed. The file (wuauclt/dllhost/searchfilterhost/wmiadap/lucallbackproxy/ieuser and others).exe is infected. Do you want to activate your antivirus software now?" I have clicked NO every time, and then every so often a box will appear in the bottom right corner of the screen that says that Win32/Nuquel.E or BankerFox.A is trying to attack. Do I want to block? I click NO. It'll also randomly open my Windows Security Center.

I have tried MANY things. I can't run HijackThis. It won't allow it to go through. I can't run any of the programs in the Virus, Spyware, and Trojan Removal thread. It blocks them all. I've only managed to run Spybot- Search and Destroy. I've also looked up several guides and tutorials on possibly removing the BankerFox and Win32/Nuquel programs but when I searched my entire laptop, there weren't any of those files in here.

I don't know what to do to save this computer. I just know that I've tried mostly everything I can think of. The biggest handicap is being unable to run antivirus applications once I've downloaded them.

What should I do?
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