A problem occurred within NTFS.SYS, the driver file that allows the system to read and write to NTFS file system drives. There may be a physical problem with the disk, or an Interrupt Request Packet (IRP) may be corrupted. Other common causes include heavy hard drive fragmentation, heavy file I/O, problems with some types of drive-mirroring software, or some antivirus software. I suggest running ChkDsk or ScanDisk as a first step; then disable all file system filters such as virus scanners, firewall software, or backup utilities. Check the file properties of NTFS.SYS to ensure it matches the current OS or SP version. Update all disk, tape backup, CD-ROM, or removable device drivers to the most current versions.
Running CHKDSK from the Windows CD
And the long way to get your desktop back( but it works)