The first thing she can do is go to "My Computer" right click her "Hard Drive" (usually C:\) click "disk cleanup" and select all temp/temporary folders and recycle bin and clean it up. Run Spybot and AdAware after that (full system scan with adaware). Go to control panel, add/remove programs and uninstall any or all of the following:
Any searchbar/toolbar except for google
Any sort of casinos or rebates programs
This should give a good start. Run spybot and adaware again. Make sure she updates them weekly at least, I check daily.
Download Hijack This from the "Hijack This Guide" in my signature and put it on your daughters computer. Close all running programs and scan the computer. Save the logfile to the desktop or something (somewhere easily accessible) and move it back to your computer and post the contents of the log here. Tell her not to remove any entries with hijack this, someone will be along to post further instructions (after you post the log) on what to remove.
Tell her not to worry, her computer is not done for, just temporarily disabled. Just follow our instructions exactly and we'll fix her up real good. She should probably stay off the internet once you get the hijack log. We do not want it changing on us then it will be pretty much impossible to clean it all out. Also when you get hijack this on her computer you should save it to a permanent directory like C:\HJT, then you can make a shortcut on the desktop. This is so the hijack this backup folders that are made won't be wiped out from the temporary folders on accident.