We're running Windows 2000 Pro on all of these machines, and when we try to open Control Panel we are prompted with this error message:
explorer.exe has generated errors and will be closed by Windows. You will need to restart the program. An error log is being created.
Then explorer restarts (everything but the wallpaper disappears momentarily), and it goes back to the regular screen but no Control Panel. The most confusing part is that if we install the same drive on certain computer models, the problem disappears. The Dell Optiplex GX100's we have seem to be the most consistent at having this bug.
Contol panel operates without a hitch in Safe Mode, but many of our clients are not computer-savvy (in fact, that is our target), so entering and exiting Safe Mode can become very confusing for them. We've pretty much exhausted our ideas (updating anti-virus/anti-spyware, editting registry several times, switching drives, etc.) so any help would be greatly appreciated!