Hi and welcome to Geeks to Go. What kind of PCI video card are you replacing? You need to remove those drivers. Use Driver Cleaner (get it at http://www.drivercleaner.net/
, it is free). If you don't know what kind of video card it is, run Belarc Advisor (search google for it, also free) and it will tell you. Once you have identified the make of your existing card, go to add/remove programs and remove the driver. Then boot into safe mode and run Driver Cleaner TWICE, each time deleting all that it finds. Then shut down, removed the existing PCI video card and install your NEW pci video card. Then boot up and install the driver for the new card, which should be on the setup cd you mentioned.