IMO
Kaspersky Anti-Virus is the best, however I don't have it on my system because it's a resource hog.
Noton is very good, but like Internet Explorer, and Windows, it's popularity has made it a target of many malware. It seems too easy to disable, and can be difficult to get working again once it's been corrupted. It catches most threats, and is the easiest on your system's resources.
Based on the logs we see, McAfee seems the worse. Many systems come preloaded with 90 days free. I suspect many users don't purchase the subscription for definitions, and that's why we see so many problems with it.
We usually recommend
AVG's Free Version. They offer the previous generation of their software. The latest version is available for purchase. It works very well, has automatic definition updates, and it's free!
Most important is to have antivirus software on every system, and keep it updated! You can find a list of programs
here.