Now let's do a little optimizing for you. You've got several antispyware programs that are all very good, but you shouldn't have them all running at the same time. Pick one these four to run in the background and either uninstall the other three, or only run them as needed.
Here are some optional fixes you can make with Hijackthis. They are not malware. These are programs that run automatically at startup. They are not necessary to be run at every startup and hog your computer's resources. Fixing these will improve boot up time and performance.
O4 - HKLM\..\Run: [AdaptecDirectCD] "C:\Program Files\Roxio\Easy CD Creator 5\DirectCD\DirectCD.exe"
O4 - HKLM\..\Run: [Microsoft Works Portfolio] C:\Program Files\Microsoft Works\WksSb.exe /AllUsers
O4 - HKLM\..\Run: [Microsoft Works Update Detection] C:\Program Files\Common Files\Microsoft Shared\Works Shared\WkUFind.exe
O4 - HKLM\..\Run: [MoneyStartUp10.0] "C:\Program Files\Microsoft Money\System\Activation.exe"
O4 - HKLM\..\Run: [WorksFUD] C:\Program Files\Microsoft Works\wkfud.exe
O4 - HKLM\..\Run: [WinampAgent] "C:\Program Files\Winamp3\winampa.exe"
O4 - HKLM\..\Run: [HP Software Update] C:\Program Files\Hewlett-Packard\HP Software Update\HPWuSchd2.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [mmtask] C:\Program Files\MusicMatch\MusicMatch Jukebox\mmtask.exe
O4 - HKLM\..\Run: [MMTray] C:\Program Files\MusicMatch\MusicMatch Jukebox\mm_tray.exe
O4 - HKLM\..\Run: [ViewMgr] C:\Program Files\Viewpoint\Viewpoint Manager\ViewMgr.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
Reboot and let me know how things are working.