I have my PSU hooked to the motherboard (in the case) and my RAM and Graphics card installed. I have my PWR lead from the case and the speaker lead (no noise yet) hooked up as well.
When I turn on the PSU, the tiny LEDs on the motherboard light up. Then, when I press the PWR button on my case, all three fans (PSU,Case,CPU) spin momentarily, then stop.
This is my first build.