You install the May 2007 Cumulative Security Update for Internet Explorer (MS07-027), and then you try to open Windows Internet Explorer 7. After you do this, the File Download – Security Warning dialog box may open, and you may receive the following message:
Do you want to save this file?
The File Download – Security Warning dialog box also refers to the "navcancl" file name. After you close this dialog box, you cannot start Internet Explorer 7.
http://support.microsoft.com/kb/937409