The interactions between your antivirus program and your computer are very complex, and require your antivirus to have nearly unrestrained access to your network, files, and programs if it is to be effective. Introducing a second such program into the mix causes conflicts when both attempt to monitor the same files at the same time. It is true that there are some viruses that certain packages don't detect, and the intuitive response is to install more Antivirus programs to fill the gap. In practice however you will slow down your system and in some cases leave it less protected than it would be with either program in place alone. Therefore I suggest that you uninstall one of your antivirus programs.
Computer slowdown can be malware related, but can also have a number of other causes. If you believe that malware issues you should post in the malware removal section, where only helpers trained to deal with malware will be able to assist and the quality of help will be much better.
Meanwhile I suggest that you perform the following to speed up the machine:
Reboot your computer after taking off the AV program.
Defragment your hard drive, which will improve the rate at which Windows Reads from and writes to your hard disk.
Clean up your startup lists, which will remove unnecessary programs from taking up RAM and CPU cycles.
Ensure that you have a significant portion of your Hard disk free.
Consider turning off some of the fancier graphics that comes on XP.
Consider turning of unnecessary services.
If you have any questions about how to do these, please ask.