1. Initial start-up is very slow, takes several minutes
2. In XP, opening folders and applications is very slow
3. Opening a browser (Firefox) takes a long time
4. Opening new tabs in the browser often fails, due to time-out
5. I hear the hard-drive being accessed frequently, even when applications aren't being loaded
Not sure if there is something going on in XP (malware?) or if it's time to replace my hard drive.