Probably not. You might go back in to ShellExView and turn on a few of the items you turned off and then restart Explorer or reboot and see if the problem comes back. Try and isolate it to a particular item and then uninstall the associated program.
Usually it's an extension or plugin that causes the problem. In Firefox it's easy to start without extensions disabled:
https://support.mozi...using-safe-mode
Then you turn them on a few at a time until you isolate it to the particular extension or plugin which is causing the problem.
Alternatively you can post in our malware forum (with OTL log - see the top post in the malware forum) and one of us can help you remove suspicious extensions and plugins.