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PC is running slow

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I am having problem with my PC it's very slow!
My nephew recently was downloading some files from Internet and from that time my Pc is slow!
I need some help to figure is this caused by some malware or other things!

This is my Hijack This log

Logfile of HijackThis v1.99.1
Scan saved at 00:25:43, on 18.06.2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\Program Files\Microsoft AntiSpyware\gcasServ.exe
C:\Program Files\UnH Solutions\IE Privacy Keeper\IEPrivacyKeeper.exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\Program Files\Microsoft AntiSpyware\gcasDtServ.exe
C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
E:\Hijack This\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = Microsoft Internet Explorer
O2 - BHO: Yahoo! Companion BHO - {02478D38-C3F9-4efb-9B51-7695ECA05670} - (no file)
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {206E52E0-D52E-11D4-AD54-0000E86C26F6} - C:\PROGRA~1\FRESHD~1\FRESHD~1\fdcatch.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O4 - HKLM\..\Run: [PCTVOICE] pctspk.exe
O4 - HKLM\..\Run: [Cmaudio] RunDll32 cmicnfg.dll,CMICtrlWnd
O4 - HKLM\..\Run: [KAVPersonal50] "C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus Personal\kav.exe" /minimize
O4 - HKLM\..\Run: [gcasServ] "C:\Program Files\Microsoft AntiSpyware\gcasServ.exe"
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [NeroCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [IE Privacy Keeper] "C:\Program Files\UnH Solutions\IE Privacy Keeper\IEPrivacyKeeper.exe" -startup
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O6 - HKCU\Software\Policies\Microsoft\Internet Explorer\Control Panel present
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra button: (no name) - {D799B0E4-BEDE-41d2-AEE0-1E3A1C4EF918} - C:\Program Files\UnH Solutions\IE Privacy Keeper\IEPrivacyKeeper.exe (HKCU)
O9 - Extra 'Tools' menuitem: IE Privacy Keeper - {D799B0E4-BEDE-41d2-AEE0-1E3A1C4EF918} - C:\Program Files\UnH Solutions\IE Privacy Keeper\IEPrivacyKeeper.exe (HKCU)
O16 - DPF: ppctlcab - http://ppupdates.ca....er/ppctlcab.cab
O16 - DPF: {2BC66F54-93A8-11D3-BEB6-00105AA9B6AE} (Symantec AntiVirus scanner) - http://security.syma...bin/AvSniff.cab
O16 - DPF: {644E432F-49D3-41A1-8DD5-E099162EEEC5} (Symantec RuFSI Utility Class) - http://security.syma...n/bin/cabsa.cab
O16 - DPF: {8AD9C840-044E-11D1-B3E9-00805F499D93} -
O16 - DPF: {B9191F79-5613-4C76-AA2A-398534BB8999} - http://us.dl1.yimg.c...utocomplete.cab
O16 - DPF: {CAFEEFAC-0015-0000-0001-ABCDEFFEDCBA} -
O23 - Service: Ati HotKey Poller - Unknown owner - C:\WINDOWS\System32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - C:\WINDOWS\system32\ati2sgag.exe
O23 - Service: kavsvc - Kaspersky Lab - C:\Program Files\Kaspersky Lab\Kaspersky Anti-Virus Personal\kavsvc.exe
O23 - Service: LexBce Server (LexBceS) - Lexmark International, Inc. - C:\WINDOWS\system32\LEXBCES.EXE
O23 - Service: PCTEL Speaker Phone (Pctspk) - Unknown owner - C:\WINDOWS\system32\pctspk.exe
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