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desktop deleted

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I turn on my computer and I have everything just fine I wait about 30 seconds and my desktop is gone and I have no permishions to any of my folders I have to run everything off off the ctl+alt+delete menu and I can't get rid of it I run spysweeper and it found vundo had respawned I can't get rid of it and it won't let me run hijackthis it has infected HKLM\software\microsoft\removerp it us part of the registry how can I delete this with out having and permishions and using the run windows(it's the only way I can open programs)
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