As alternative browsers become more popular, so too do they become more attractive targets for badguys. We've seen this with Firefox, and obviously now with Chrome, which has 5 of the 9 listed "High Vulnerabilities" in this report. I am not saying Chrome users need to flock back to Internet Explorer, but I am saying the excuse that IE is unsafe is no longer a valid reason to abandon it.
In any case, it is regardless the browser of choice, it is paramount users keep their systems current with the latest patches and updates, to include XP SP3, use a real-time anti-malware solution, a firewall, and avoid risky practices like filesharing of copyrighted materials via P2P or torrents, visiting illegal porn or gambling sights, or opening downloads and attachments without scanning first.