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Complex malware infection beyond my understanding

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I'm a fairly experienced and competent user and I'm absolutely convinced my system is infected. I ran MalwareBytes, SpyBot, CCleaner, and scanned with AVG. It managed to remove a few Tracking Cookies here and there, but I know theres much more than that.

A system restore was performed, yet a host of problems still remain like:
(1) Google chrome won't load a single page, yet all other browsers operate fine
(2) When I try to run .exe files, I get an error saying "The Pipe State is Invalid"
(3) I spotted winlogon.exe and csrss.exe (which i've never seen before) using the task manager and can't end them, I get another error saying "Access is denied". It's also worth noting that the Description and User Name boxes are left blank. I can however end every other process with ease. On a balance of probability, these two are malicious.

I followed the instructions provided on this forum such as to download the GMER rootkit thing, OTL, and ComboFix, but as (2) says, "The pipe state is invalid". I have absolutely no clue where to go from here.

I'd appreciate any help I can get, thanks!

Edited by purplepigeon, 15 October 2010 - 01:48 AM.

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